Modeling and simulation of isothermal reactive liquid chromatography for two component elution-effects of core-shell particles
In this work, semi-analytical solutions obtained by a combination of analytical and numerical procedure based on the numerical Hankel and Laplace transform inversions and solution of same model using high resolution finite volume numerical method are presented. These solutions are obtained for two-dimensional general rate models for isothermal liquid chromatographic reactors of cylindrical geometry packed with core-shell particles for an irreversible chemical reaction. This task is aimed at investigating the performance of the two-dimensional chromatography column under isothermal operating condition with the use of core-shell particles. The semi-analytical solutions are obtained considering the first-type and second-type boundary conditions. The use of core-shell particles is observed to produce less diffusive and sharper peaks but separation of chemical components is not significantly improved when compared with the results for porous particles.
Copyright (c) 2022 Ugochukwu David Uche, Mercy Uche, Folakemi Okafor, Kate Utalor
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, adaptation, and reproduction in any medium, provided that the original work is properly cited.